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Epidermal growth factor EGFR can also interact with IGF-1R, and loss of EGFR leads to depletion of IGF-1R [11]

The production of ROS can be induced by exposure to various factors, such as heavy metals, tobacco, smoke, drugs, exogenous substances, pollutants, and radiation [59]

It is also involved in energy production, via roles in fatty acid and amino acid metabolism

Glutathione can prevent and repair oxidative damage by capturing free radicals throughout the body and recharging other antioxidants, thus preventing chronic disease and inflammation

The l-carnitine used in our experiments is a water-soluble antioxidant substance that has a good effect on the treatment of male varicocele, idiopathic oligoasthenospermia and reproductive inflammation